GeneticsbioRxiv
GWIS: Genome Wide Inferred Statistics for non-linear functions of multiple phenotypes
Harold Nieuwboer, Rene Pool, Conor V Dolan…·Michel G Nivard
The paper introduces GWIS, a method to approximate GWAS summary statistics for complex phenotypes using existing GWAS data, and applies it to study BMI and psychiatric disorders.
DOI 10.1016/j.ajhg.2016.07.020