Evolutionary BiologyNature Ecology & EvolutionPeer-reviewed
Sequence Entropy and the Absolute Rate of Amino Acid Substitutions
Richard A Goldstein, David D Pollock
This study develops a statistical mechanics theory to predict amino acid substitution rates based on sequence entropy and physicochemical properties, showing that substitution rates are determined by stability and not population size.
DOI 10.1038/s41559-017-0338-9