GeneticsG3 Genes Genomes GeneticsPeer-reviewed
Identification of essential genes in Caenorhabditis elegans through whole genome sequencing of legacy mutant collections
Erica Li-Leger, Richard Feichtinger, Stéphane Flibotte…·Donald G. Moerman
This study identifies 58 essential genes in C. elegans using whole genome sequencing of maternal-effect lethal and sterile mutants, revealing novel alleles and functional roles in embryonic development and fertilization.