GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior
Chihiro Nakamoto, Meiko Kawamura, Ena Nakatsukasa…·Kenji Sakimura
This study shows that GluD1 knockout mice exhibit impaired fear memory, reduced sociability, and enhanced depressive-like behavior, with antidepressant effects observed with serotonin reuptake inhibitors.