Evolutionary BiologybioRxivPreprint
Cross-species neural co-culture uncovers metabolic signatures of cellular crosstalk
Katherine Rickelton, Rithvik Sandiri, Jessica Roy…·Courtney C. Babbitt
The paper develops a cross-species co-culture model of astrocytes and neurons from human and chimpanzee iPSCs to study metabolic differences and finds human co-cultures are more metabolically active, with astrocytes driving species-specific metabolic differences.
DOI 10.64898/2026.07.31.741820