NeurosciencebioRxivPreprint
Citrullination of TDP-43 is a key post-translation modification associated with structural and functional changes and progressive pathology in TDP-43 mouse models and human proteinopathies
Christopher Saunders, Patricia Rocha-Rangel, Rohan Desai…·Maj‐Linda B. Selenica
This study identifies citrullination as a novel irreversible post-translational modification of TDP-43 linked to structural changes, aggregation, and pathology in TDP-43 proteinopathies.
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