NeuroscienceeLifePeer-reviewed
Simultaneous Brain, Brainstem and Spinal Cord pharmacological-fMRI reveals endogenous opioid network interactions mediating attentional analgesia
Valeria Oliva, Ron Hartley-Davies, Rosalyn Moran…·Jonathan CW Brooks
The paper uses pharmacological-fMRI to show that attentional analgesia in humans is mediated by opioidergic pathways from ACC to PAG and RVM, which suppress spinal nociceptive activity.