Author

Roni R. Hyman

Broad Institute

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Cancer Biology· 1

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Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

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Andrew Castillo· 1 shared Daniel ZeveiD· 1 shared David T. BreaultiD· 1 shared Ena Oreskovic· 1 shared Jason Daniel BuenrostroiD· 1 shared Karina Sharma· 1 shared Lety Ojeda-MironiD· 1 shared Ömer H. YilmaziD· 1 shared

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1 shared paperCancer Biology

Andrew Castillo

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 13, 2025

Clonal memory of colitis accumulates and promotes tumor growth

Surya Nagaraja, Lety Ojeda-Miron, Ruochi Zhang…·Jason Daniel Buenrostro

The paper shows that colitis leaves an epigenetic memory in colonic stem cells that promotes tumor growth by enhancing regenerative gene programs and AP-1 activity.

DOI 10.1101/2025.02.13.638099

mousescRNA-seq

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