Cancer BiologyJournal of Biological ChemistryPeer-reviewed
Large extracellular vesicles regulate endothelial angiogenic potential via paracrine and autocrine signaling
Crislyn D’Souza‐Schorey, Rose Nguyen, Alanna Sedgwick…·Crislyn D’Souza-Schorey
This study shows that large extracellular vesicles from melanoma promote angiogenic phenotypes in endothelial cells through paracrine and autocrine signaling, contributing to resistance to anti-angiogenic therapies.
DOI 10.1016/j.jbc.2026.111193