Author

Ruthie Mulvaney

Vanderbilt University

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:Xenopus· 1

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David CorteziD· 1 shared David T Long· 1 shared James M. DewariD· 1 shared Matthew T. CranfordiD· 1 shared Sara C. Conwell· 1 shared Steven N Dahmen· 1 shared

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1 shared paperBiochemistry

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintMar 3, 2025

Resolution of collapsed forks is separate from completion of DNA synthesis

Sara C. Conwell, Steven N Dahmen, Matthew T. Cranford…·James M. Dewar

The paper shows that replication fork collapse at SSBs leads to seDSBs resolved by homologous recombination, but DNA synthesis downstream is inefficient, while deDSBs allow efficient synthesis without recombination.

DOI 10.1101/2025.03.03.641087

Xenopusexperimental assay

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