Sp Transcription Factors Establish the Signaling Environment in the Neuromesodermal Progenitor Niche During Axial Elongation
Ravindra B. Chalamalasetty, Haley Tran, Ryan Kelly…·Terry P. Yamaguchi
The paper identifies Sp5/8 as essential regulators of neuromesodermal progenitor maintenance through their role in sustaining Wnt/Fgf signaling and repressing retinoic acid activity.