BiophysicsMolecular Biology and EvolutionPeer-reviewed
Connecting the sequence-space of bacterial signaling proteins to phenotypes using coevolutionary landscapes
Ryan R. Cheng, Olle Nordesjö, Ryan L. Hayes…·Faruck Morcos
The paper constructs a Potts model to predict how mutations affect TCS protein interactions and validates it against experimental data on PhoQ kinase variants.
DOI 10.1093/molbev/msw188