ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewed
Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells
Anders W. Matson, Robert Hullsiek, Kate J. Dixon…·Bruce K. Walcheck
This study shows that an ADAM17-blocking antibody enhances IL-15-mediated NK cell activation and proliferation through CD16A and CD137, with potential therapeutic applications in cancer.
13 citations