BioengineeringbioRxiv
Force-mediated recruitment and reprogramming of healthy endothelial cells drive vascular lesion growth
A. Shapeti, J. Barrasa Fano, A. R. Abdel Fattah…·H. Van Oosterwyck
This study reveals how CCM2-silenced endothelial cells use mechanical forces to recruit and reprogram wild-type cells, driving vascular lesion growth through force-guided invasion and cellular reprogramming.
DOI 10.1038/s41467-024-52866-6