H. Van Oosterwyck

This study assesses the accuracy and efficiency of 3D traction force microscopy (TFM) by evaluating traction reconstruction from synthetic ground truth data under various conditions.

This study uses synthetic fibrous hydrogels to investigate cell-matrix mechanical interactions and their impact on cellular behavior.

TFMLAB is a MATLAB toolbox for 4D traction force microscopy that provides an easy-to-use workflow for analyzing in vitro systems.

The paper shows that CCM2-deficient endothelial cells undergo mechano-dependent reprogramming into SASP, recruiting endothelial and immune cells.

This paper develops an in silico framework to validate 3D Traction Force Microscopy methods, showing the inverse method outperforms the forward method in accuracy for traction recovery.

The paper shows that applying active mechanical forces to human neural tube organoids enhances their patterning and growth through temporally restricted mechanoregulation.

This paper develops a computational model of cell pairs on patterned substrates to study how intercellular adhesion stiffness influences cell decoupling on stiff substrates.

This paper develops a computational model to study how actin protrusion dynamics influence 3D cell migration through a degradable viscoelastic extracellular matrix, revealing key factors affecting migration efficiency and speed.