Author

S. A. Grupp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. H. June· 2 shared D. M. Barrett· 2 shared C. Burudpakdee· 1 shared C. R. Good· 1 shared D. Kim· 1 shared E. J. Orlando· 1 shared H. Bassiri· 1 shared H. Sun· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

C. H. June

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Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivApr 29, 2021

Distinct bioenergetic features of human invariant natural killer T (iNKT) cells enable retained functions in nutrient-deprived states

P. Khurana, C. Burudpakdee, S. A. Grupp…·H. Bassiri

This study identifies distinct bioenergetic features of human iNKT cells that enable their survival and effector function in nutrient-deprived conditions compared to conventional T cells.

DOI 10.3389/fimmu.2021.700374

humanbulk RNA-seq

ImmunologybioRxivApr 15, 2021

Single-cell antigen-specific activation landscape of CAR T infusion product identifies determinants of CD19 positive relapse in patients with ALL

Z. Bai, S. Woodhouse, D. Kim…·R. Fan

The paper analyzes single-cell data from CAR T infusion products to identify factors associated with CD19-positive relapse in ALL patients.

DOI 10.1126/sciadv.abj2820

humanscRNA-seq

ImmunologybioRxivPreprintMay 5, 2019

Impaired tumor death receptor signaling drives resistance to CAR T cell therapy

N. Singh, O. Shestova, P. Ravikumar…·M. Ruella

This study identifies impaired death receptor signaling as a driver of resistance to CAR T cell therapy in B-cell leukemia by showing its role in tumor survival and T cell dysfunction.

DOI 10.1101/627562

mousehuman