BiochemistrybioRxivPreprint
ApoC-III helical structure determines its ability to bind plasma lipoproteins and inhibit Lipoprotein Lipase-mediated triglyceride lipolysis.
C. Vitali, S. Stankov, S. A. Khetarpal…·D. J. Rader
This study investigates how structural changes in apoC-III affect its interaction with lipoproteins and LPL activity, revealing that hydrophilic-lipophilic properties of alpha helices modulate triglyceride levels.
DOI 10.1101/2020.07.02.183178