MicrobiologyPLOS PathogensPeer-reviewed
Repurposing the Streptococcus mutans CRISPR-Cas9 System to Understand Essential Gene Function
R. C. Shields, A. R. Walker, N. Maricic…·R. A. Burne
The paper develops a CRISPR interference tool for Streptococcus mutans to study essential genes, identifying growth defects and phenotypes in 77% of targeted strains.
DOI 10.1371/journal.ppat.1008344