Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
Y. Nakajima-Takagi, M. Oshima, J. Takano, S. Koide, N. Itokawa, S. Uemura, M. Yamashita, S. Andoh, K. Aoyama, Y. Isshiki, D. Shinoda, A. Saraya, F. Arai, K. Yamaguchi, Y. Furukawa, , A. Iwama
This study identifies PRC1.1 as a regulator of homeostatic and emergency myelopoiesis, showing its role in balancing myeloid differentiation and preventing transformation.
bioRxiv · Sep 7, 2022Immunology