Y. Furukawa

The paper shows that microbiome ssRNA activates TLR13 in hepatic macrophages to drive tissue-protective responses, leading to resistance against acute liver injury in Rnaset2-/- mice.

This study identifies TLR7/8 as drivers of histiocytosis in SLC29A3 disorders by responding to lysosomal nucleoside stress and enhancing monocyte proliferation and phagocyte maturation.

This paper quantitatively analyzes calcium oxalate monohydrate and dihydrate in kidney stones using FTIR, PXRD, and micro-CT to understand their formation mechanisms.

This study investigates pulmonary lesions in rats exposed to titanium dioxide nanoparticles, identifying a new lesion type called pulmonary dust foci associated with pneumoconiosis-like effects.

This study identifies PRC1.1 as a regulator of homeostatic and emergency myelopoiesis, showing its role in balancing myeloid differentiation and preventing transformation.

This study shows that overexpressing adenylate kinase 1 in medaka fish increases locomotor activity, which is temperature-dependent.

This study investigates the dose-response relationship of pulmonary disorders caused by inhalation of CWAAP-A in rats, finding a LOAEC of 1 mg/m3 and reversible damage at 1 mg/m3 with gender differences in recovery.

This study shows titanium dioxide nanoparticles do not cause lung fibrosis or cancer in rasH2 mice after 26 weeks of inhalation exposure up to 32 mg/m3.

The paper expresses and purifies FLT3-ITD protein using a silkworm-baculovirus system and identifies two potent inhibitors through an inhibition assay.

This study examines lung damage in rats exposed to cross-linked water-soluble acrylic acid polymers (CWAAPs) via inhalation and intratracheal instillation, finding similar pathological outcomes between exposure routes.