Placental inflammation leads to abnormal embryonic heart development
E. J. Ward, S. Bert, S. Fanti, N. P. Dufton, K. M. Malone, R. T. Maughan, F. Prin, L.-K. Volpato, A. P. Piovesan, M. Perretti, F. M. Marelli-Berg, S. Nadkarni
This study shows that placental inflammation caused by neutrophils leads to abnormal embryonic heart development and postnatal cardiac dysfunction, which can be mitigated by reducing placental inflammation.
bioRxiv · Mar 10, 2022Immunology