Author

S. Betrand

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Biology Disciplines

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

C. Palles· 1 shared C.-C. Pai· 1 shared E. Heitzer· 1 shared E. Vazquez· 1 shared I. Soriano· 1 shared I. Tomlinson· 1 shared N. de Leon· 1 shared S. Cotterill· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. Palles

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1 paper

Recent·Most cited

Cancer BiologyPLOS GeneticsPeer-reviewedJul 6, 2021

Expression of the cancer-associated DNA polymerase ϵ P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication

I. Soriano, E. Vazquez, N. de Leon…·S. Kearsey

This paper models the POLE-P286R mutation in fission yeast, showing it causes hypermutation, DNA replication defects, and dependence on translesion synthesis polymerases.

DOI 10.1371/journal.pgen.1009526

yeastDNA methylation

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