Author

E. Heitzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

S. Perakis· 2 shared T. Moser· 2 shared A. C. Riddick· 1 shared A. Carracedo· 1 shared A. Gerger· 1 shared A. L. Riediger· 1 shared A. Matakidou· 1 shared A. Orlova· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

S. Perakis

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Author profile →

4 papers

Recent·Most cited

STAT3 restricts prostate cancer metastasis and antiandrogen resistance by controlling LKB1/CREB signaling pathway

J. Pencik, C. Philippe, M. Schlederer, M. Pecoraro, S. Grund-Groeschke, W. J. Li, A. Tracz, I. Heidegger, S. Lagger, K. Trachtova, M. Oberhuber, E. Heitzer, O. Osman, H. A. Neubauer, B. Wingelhofer, , C. McKinney

This study identifies STAT3's role in restricting prostate cancer metastasis and antiandrogen resistance by regulating the LKB1/CREB signaling pathway in mouse models and human patients.

bioRxiv · Aug 25, 2022 · PreprintCancer Biology

Expression of the cancer-associated DNA polymerase ϵ P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication

I. Soriano, E. Vazquez, N. de Leon, S. Betrand, E. Heitzer, S. Toumazou, C. Palles, C.-C. Pai, T. Humphrey, I. Tomlinson, S. Cotterill, S. Kearsey

This paper models the POLE-P286R mutation in fission yeast, showing it causes hypermutation, DNA replication defects, and dependence on translesion synthesis polymerases.

bioRxiv · Apr 6, 2021Cancer Biology

Comprehensive characterisation of cell-free tumour DNA in plasma and urine of patients with renal tumours

C. G. Smith, T. Moser, J. Burge, M. Eldridge, A. L. Riediger, F. Mouliere, D. Chandrananda, K. Heider, J. C. Wan, A. Y. Warren, J. Morris, I. Hudecova, W. N. Cooper, T. J. Mitchell, D. Gale, , G. D. Stewart

The paper uses sequencing methods to show that cell-free tumour DNA levels are low in renal cancer but can still be informative with improved detection strategies.

bioRxiv · Sep 11, 2019 · PreprintCancer Biology

Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection of cancer

P. Ulz, S. Perakis, Q. Zhou, T. Moser, J. Belic, I. Lazzeri, A. Wölfler, A. Zebisch, A. Gerger, G. Pristauz, E. Petru, B. White, C. E. S. Roberts, J. St. John, M. G. Schimek, , M. R. Speicher

This study infers tumor cell-specific transcription factor binding from cell-free DNA to predict tumor subtypes and detect cancer early.

bioRxiv · Mar 31, 2019 · PreprintCancer Biology