Age-related changes to macrophages are detrimental to fracture healing
D. Clark, S. Brazina, F. Yang, D. Hu, E. Niemi, T. Miclau, M. Nakamura, R. Marcucio
This study shows that age-related changes in macrophages impair fracture healing in old mice, and depleting these macrophages improves healing outcomes.
bioRxiv · Jul 31, 2019 · PreprintImmunology