Author

S. C. Ems-McClung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

C. E. Walczak· 2 shared A. L. Yount· 1 shared C. Moe· 1 shared C. Walczak· 1 shared H. Zong· 1 shared J. C. Smith· 1 shared J. Pilrose· 1 shared J. R. Stout· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

C. E. Walczak

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Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivMay 31, 2023

MCAK Inhibitors Induce Aneuploidy in Triple Negative Breast Cancer Models

J. C. Smith, S. Husted, J. Pilrose…·C. E. Walczak

This study identifies three MCAK inhibitors that induce aneuploidy in TNBC cells, reduce clonogenic survival, and sensitize cells to paclitaxel.

DOI 10.3390/cancers15133309

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintMar 30, 2022

Importin alpha/βeta Promote Kif18B Microtubule Association to Spatially Control Microtubule Destabilization

S. Shrestha, S. C. Ems-McClung, M. A. Hazelbaker…·C. Walczak

This study shows importin alpha/beta enhance Kif18B microtubule association, spatially controlling MT destabilization, while EB1 has a distinct role in this process.

DOI 10.1101/2022.03.30.486445

experimental assaycell signaling & trafficking

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Cell BiologybioRxivApr 30, 2020

Spatial Regulation of MCAK Promotes Cell Polarization and Focal Adhesion Turnover to Drive Robust Cell Migration

H. Zong, M. Hazelbaker, C. Moe…·C. E. Walczak

This study shows that MCAK's spatial distribution regulates cell migration by affecting MT dynamics, cell polarization, and focal adhesion turnover in RPE-1 cells.

DOI 10.1091/mbc.e20-05-0301

𝕏 PostBluesky