mTOR Inhibition Suppresses Salinomycin-Induced Ferroptosis in Breast Cancer Stem Cells by Ironing Out Mitochondrial Dysfunctions
E. Cosialls, E. Pacreau, S. Ceccacci, R. Elhage, C. Duruel, C. Desterke, K. Roger, C. Guerrera, R. Ducloux, S. Souquere, G. Pierron, I. Nemazanyy, M. Kelly, E. Dalmas, Y. Chang, , A. Hamai
The paper shows that mTOR inhibition reduces Salinomycin-induced ferroptosis in breast cancer stem cells by modulating iron flux and mitochondrial function.
bioRxiv · May 2, 2023Cancer Biology