Late killing of Plasmodium berghei in the liver by an anti-circumsporozoite protein monoclonal antibody
M. C. Aguirre-Botero, O. Pacios, S. Celli, E. Aliprandini, A. Gladston, J.-M. Thiberge, P. Formaglio, R. Amino
The paper shows that the 3D11 anti-CSP monoclonal antibody neutralizes Plasmodium berghei sporozoites in the liver after several hours, inhibiting motility and leading to parasite killing.
bioRxiv · Apr 30, 2024Microbiology