MAIT cells drive chronic inflammation in a genetically diverse murine model of spontaneous colitis.
L. Loh, D. Orlicky, A. Spengler, C. Levens, S. Celli, J. Domenico, J. Klarquist, J. Onyiah, J. Matsuda, K. A. Kuhn, L. Gapin
This study investigates the role of MAIT cells in a genetically diverse mouse model of spontaneous colitis, finding that MAIT cells drive chronic inflammation and colonic pathology.
bioRxiv · Nov 29, 2023 · PreprintImmunology