S. Chadha

The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer

This paper shows that MARCHF8 stabilizes HPV E7 by degrading CUL1 and UBE2L3, preventing E7 degradation in HPV+ HNC cells.

HPV E6 upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer