Author

S. Cinque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

E. Leucci· 3 shared O. Bechter· 3 shared E. Demesmaeker· 2 shared J. Pozniak· 2 shared J.-C. Marine· 2 shared P. Karras· 2 shared R. Vendramin· 2 shared S. Adnane· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

E. Leucci

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The assembly of cancer-specific ribosomes by the lncRNA LISRR suppresses melanoma anti-tumour immunity

S. Cinque, Y. Verheyden, S. Adnane, A. Marino, V. Katopodi, E. Demesmaeker, Z. Knezevic, S. Hanache, R. Vendramin, A. Cuomo, J. Pozniak, A. C. Calabuig, S. Tabruyn, O. Bechter, M. F. Baietti, , E. Leucci

This study identifies LISRR, a cancer-specific lncRNA that assembles immunosuppressive ribosomes in melanoma, suppressing anti-tumour immunity and resistance to immune checkpoint blockade.

bioRxiv · Jan 6, 2023 · PreprintCancer Biology

A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma

J. Pozniak, D. Pedri, E. Landeloos, Y. Van Herck, A. Antoranz, P. Karras, A. Nowosad, S. Makhzami, G. Bervoets, M. Dewaele, L. Vanwynsberghe, S. Cinque, S. Kint, K. Vandereyken, T. Voet, , J.-C. Marine

This study identifies a TCF4/BRD4-dependent regulatory network that drives cross-resistance to ICB and targeted therapy in melanoma by analyzing scRNA-seq data from a longitudinal cohort.

bioRxiv · Aug 11, 2022 · PreprintCancer Biology

Activation of the Integrated Stress Response in drug-tolerant melanoma cells confers vulnerability to mitoribosome-targeting antibiotics.

R. Vendramin, A. Konnova, S. Adnane, S. Cinque, V. Katopodi, Z. Knezevic, P. Karras, E. Demesmaeker, F. M. Bosisio, L. Rizzotto, O. Bechter, J.-C. Marine, E. Leucci

This study shows that activating the Integrated Stress Response in drug-tolerant melanoma cells makes them vulnerable to mitoribosome-targeting antibiotics, offering a new therapeutic strategy.

bioRxiv · Jun 26, 2020Cancer Biology

Hydrogel mechanical properties are more important than osteoinductive growth factors for bone formation with MSC spheroids

J. Whitehead, K. E. Griffin, C. E. Vorwald, M. Gionet-Gonzales, S. Cinque, K. Leach

This study shows that viscoelastic hydrogel properties enhance bone formation by MSC spheroids more than BMP-2 growth factors.

bioRxiv · Mar 10, 2020 · PreprintBioengineering