Author

S. Constable

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

C. M. Ott· 2 shared J. Lippincott-Schwartz· 2 shared K. White· 2 shared S. Mukhopadhyay· 2 shared A. L. Lemire· 1 shared A. Lim· 1 shared T. Nguyen· 1 shared W.-C. A. Lee· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

C. M. Ott

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2 papers

Recent·Most cited

Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

S. Constable, C. M. Ott, A. L. Lemire, K. White, A. Lim, J. Lippincott-Schwartz, S. Mukhopadhyay

The paper identifies a programmed cilia deconstruction pathway in cerebellar granule cells during neurogenesis, showing decreased cilia maintenance and centriole capping prevent cilia regrowth and dysregulated signaling.

bioRxiv · Dec 7, 2023Cell Biology

Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons

C. M. Ott, S. Constable, K. White, T. Nguyen, W.-C. A. Lee, J. Lippincott-Schwartz, S. Mukhopadhyay

The paper investigates ciliary dynamics in differentiating granule cell neurons, finding that cilia are deconstructed intracellularly and do not reform in adult neurons.

bioRxiv · Dec 7, 2023 · PreprintCell Biology