Author

C. M. Ott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 4

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Assay:electronic health records· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. Lippincott-Schwartz· 4 shared K. White· 2 shared S. Constable· 2 shared S. Mukhopadhyay· 2 shared W.-C. A. Lee· 2 shared A. L. Bodor· 1 shared A. L. Lemire· 1 shared A. Lim· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersCell Biology

J. Lippincott-Schwartz

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4 papers

Recent·Most cited

Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

S. Constable, C. M. Ott, A. L. Lemire, K. White, A. Lim, J. Lippincott-Schwartz, S. Mukhopadhyay

The paper identifies a programmed cilia deconstruction pathway in cerebellar granule cells during neurogenesis, showing decreased cilia maintenance and centriole capping prevent cilia regrowth and dysregulated signaling.

bioRxiv · Dec 7, 2023Cell Biology

Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons

C. M. Ott, S. Constable, K. White, T. Nguyen, W.-C. A. Lee, J. Lippincott-Schwartz, S. Mukhopadhyay

The paper investigates ciliary dynamics in differentiating granule cell neurons, finding that cilia are deconstructed intracellularly and do not reform in adult neurons.

bioRxiv · Dec 7, 2023 · PreprintCell Biology

Nanometer-scale views of visual cortex reveal anatomical features of primary cilia poised to detect synaptic spillover

C. M. Ott, R. Torres, T.-S. Kuan, A. T. Kuan, J. Buchanan, L. Elabbady, S. Seshamani, A. L. Bodor, F. C. Collman, D. D. Bock, W.-C. A. Lee, N. Macarico da Costa, J. Lippincott-Schwartz

This study examines primary cilia in mouse visual cortex using electron microscopy, revealing their distribution, structure, and proximity to synapses.

bioRxiv · Oct 31, 2023Cell Biology

Transcriptional reprogramming in fused cells is triggered by plasma-membrane diminution

D. Feliciano, I. Espinosa-Medina, A. Weigel, K. M. Milano, Z. Tang, T. Lee, H. J. Kliman, S. M. Guller, C. M. Ott, J. Lippincott-Schwartz

The paper shows that cell fusion triggers differentiation through plasma-membrane diminution, leading to transient cell starvation and activation of AMPK, which inhibits YAP1 and causes cell-cycle arrest.

bioRxiv · Nov 6, 2019 · PreprintCell Biology