Structure of the teneurin-latrophilin complex: Alternative splicing controls synapse specificity by a novel mechanism
J. Li, Y. Xie, S. Cornelius, X. Jiang, S. P. Kordon, R. Sando, M. Pan, K. Leon, T. C. Sudhof, M. Zhao, D. Arac
The paper reports the cryo-EM structure of the Tenm2-Lphn3 complex and shows how alternative splicing regulates synapse specificity by affecting access to the Lphn-binding site.
bioRxiv · Jan 13, 2020Biochemistry