BiochemistrybioRxivPreprint
Mechanistic insights into the functioning of GMP synthetase: a two-subunit, allosterically regulated, ammonia tunnelling enzyme
S. Shivakumaraswamy, S. Kumar, A. Bellur…·H. Balaram
This paper presents a mechanistic model of MjGMPS, a two-subunit GMP synthetase, using biochemical experiments, crystal structures, and cross-linking mass spectrometry to elucidate ammonia tunneling and allostery.
DOI 10.1101/2022.02.27.481963