Molecular insights into the interaction between a disordered protein and a folded RNA
R. Mitra, E. T. Usher, S. Dedeoglu, M. J. Crotteau, O. A. Fraser, N. H. Yannawar, V. V. Gadkari, B. T. Ruotolo, A. S. Holehouse, L. Salmon, S. A. Showalter, J. C. Bardwell
This study characterizes the RNA-binding properties of a disordered protein, SERF, and shows that binding to RNA causes modest global compaction without inducing structural changes in either molecule.
bioRxiv · Jun 12, 2024Biochemistry