Genome-Wide Epigenomic Profiling of Primary Non-Small Cell Lung Cancer Reveals Specific and Recurrent DNA Methylation Alterations in Smoker Versus Never-Smoker Patients
J. A. Karlow, E. C. Pehrsson, X. Xing, M. Watson, S. Devarakonda, R. Govindan, T. Wang
This study identifies recurrent DNA methylation alterations in primary non-small cell lung cancer samples from smokers and never-smokers, highlighting differences in hypomethylation patterns and their association with oncogenes and transcription factor binding motifs.
bioRxiv · Oct 6, 2022 · PreprintCancer Biology