Evolution of regulatory signatures in primate cortical neurons at cell type resolution
A. Kozlenkov, M. W. Vermunt, P. Apontes, J. Li, K. Hao, C. C. Sherwood, P. R. Hof, J. J. Ely, M. Wegner, E. A. Mukamel, M. P. Creyghton, E. V. Koonin, S. Dracheva
This study identifies cell-type-specific regulatory changes in human, chimpanzee, and rhesus macaque cortical neurons, revealing human-specific regulatory elements linked to language and psychiatric disorders.
bioRxiv · Jul 24, 2020Evolutionary Biology