M. Wegner

The Effects of Acute Coordinative vs. Acute Endurance Exercise on the Cortisol Concentration

This study compares cortisol responses to acute coordinative and endurance exercise, finding higher cortisol release after coordinative exercise.

Targeted protein degradation via intramolecular bivalent glues

This paper introduces intramolecular bivalent glues (IBGs) as a new method for targeted protein degradation, showing they enhance ubiquitination by bridging protein domains and improving degradation efficiency.

Divergence in bacterial ecology is reflected by difference in population genetic structure, phage-predator load and host range

The paper compares two marine bacterial populations and their phages, finding differences in genetic structure, phage predation pressure, and infection network architecture due to ecological and genetic factors.

Genetic determinism of phage-bacteria coevolution in natural populations

The paper investigates phage-bacteria coevolution in natural populations, finding that phage and host genomes exhibit gene content variation and that negative-frequency dependent selection drives coevolutionary dynamics.

Combinatorial CRISPR screening reveals functional buffering in autophagy

This study uses combinatorial CRISPR screening to identify gene interactions in autophagy, revealing functional buffering and redundant gene circuits.

Evolution of regulatory signatures in primate cortical neurons at cell type resolution

This study identifies cell-type-specific regulatory changes in human, chimpanzee, and rhesus macaque cortical neurons, revealing human-specific regulatory elements linked to language and psychiatric disorders.

Deciphering the Regulatory Landscape of γδ T Cell Development by Single-Cell RNA-Sequencing

This study uses single-cell RNA-sequencing to uncover the developmental trajectory of γδ T cells, identifying c-MAF as a key regulator of IL-17-producing γδ T cell differentiation.