Structure-based humanization of a therapeutic antibody for Multiple Myeloma
The paper describes a method to humanize a therapeutic antibody for Multiple Myeloma using structural information to optimize binding affinity while minimizing antigenicity.
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The paper describes a method to humanize a therapeutic antibody for Multiple Myeloma using structural information to optimize binding affinity while minimizing antigenicity.
A. Moreira-Soto, C. Walzer, G. A. Czirjak…·A. D. Greenwood
The paper tests deer samples from Germany and Austria for SARS-CoV-2 exposure and finds no evidence of infection during the pandemic.
S. F. Marino, R. Kettritz, U. Jerke…·O. Daumke
This study shows that disrupting the CD177:PR3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation in ANCA-associated vasculitis.
V. Fabricius, J. Lefebre, H. Geertsema…·H. Ewers
The paper develops an optimized method for labeling nanobodies with DNA oligomers for DNA-PAINT, enabling efficient and straightforward superresolution imaging.