Author

S. Fleishman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Barnea· 1 shared A. Ben-David· 1 shared A. Elazar· 1 shared A. Mechaly· 1 shared A. Tennenhouse· 1 shared A. Torgeman· 1 shared D. Listov· 1 shared E. Diamant· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. Barnea

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3 papers

Recent·Most cited

Computational design of BclxL inhibitors that target transmembrane domain interactions

G. Duart, A. Elazar, J. Weinstein, L. Gadea-Salom, J. Ortiz-Mateu, S. Fleishman, I. Mingarro, L. Martinez-Gil

This study develops a computational method to design inhibitors targeting transmembrane domain interactions of BclxL, demonstrating their ability to block anti-apoptotic effects.

bioRxiv · Nov 9, 2022Biochemistry

The C-terminal tail of CSNAP attenuates the CSN complex

M. G. Füzesi-Levi, G. Ben-Nissan, D. Listov, Z. Hayouka, S. Fleishman, M. Sharon

The paper shows that a C-terminal peptide from CSNAP can displace CSNAP from the CSN complex, reducing CSN activity and CRL function, suggesting a new therapeutic approach.

bioRxiv · Jul 18, 2022Biochemistry

Isolation and characterization of a highly specific monoclonal antibody targeting the botulinum neurotoxin type E exposed SNAP-25 neoepitope

A. Mechaly, E. Diamant, R. Alcalay, A. Ben-David, E. Dor, A. Torgeman, A. Barnea, M. Girshengorn, L. Levin, E. Epstein, A. Tennenhouse, s. Fleishman, R. Zichel, O. Mazor

This paper isolates a highly specific monoclonal antibody that detects the BoNT/E-cleaved SNAP-25 neoepitope with ultra-high affinity and no cross-reactivity.

bioRxiv · Sep 16, 2021 · PreprintBiochemistry