Author

J. Weinstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Animal Behavior & Cognition· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:protein structure· 2 Organism:Arabidopsis· 1 Assay:behavioral assay· 1

Frequent Co-Authors

S. J. Fleishman· 2 shared A. C. Leonard· 1 shared A. Elazar· 1 shared A. Erbse· 1 shared A. Shimon· 1 shared C. M. Boldt· 1 shared C. Schultz· 1 shared D. Bradley· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBiochemistry

S. J. Fleishman

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Author profile →

5 papers

Recent·Most cited

Multiple behavioral mechanisms shape development in a highly social cichlid fish

I. P. Harmon, E. A. McCabe, M. R. Vergun, J. Weinstein, H. L. Graves, C. M. Boldt, D. Bradley, J. Lee, J. M. Maurice, T. K. Solomon-Lane

The paper investigates how early-life social experiences affect adult behavior and stress responses in Astatotilapia burtoni cichlid fish, finding distinct behavioral syndromes linked to social partner numbers and group stability.

bioRxiv · Apr 14, 2023 · PreprintAnimal Behavior & Cognition

Computational design of BclxL inhibitors that target transmembrane domain interactions

G. Duart, A. Elazar, J. Weinstein, L. Gadea-Salom, J. Ortiz-Mateu, S. Fleishman, I. Mingarro, L. Martinez-Gil

This study develops a computational method to design inhibitors targeting transmembrane domain interactions of BclxL, demonstrating their ability to block anti-apoptotic effects.

bioRxiv · Nov 9, 2022Biochemistry

A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants

S. E. Farley, J. Kyle, H. Leier, L. M. Bramer, J. Weinstein, T. A. Bates, J.-Y. Lee, T. O. Metz, C. Schultz, F. Tafesse

The paper identifies glycerolipid biosynthesis as a conserved host dependency factor for SARS-CoV-2 by mapping lipid metabolism changes across variants.

bioRxiv · Feb 14, 2022Microbiology

Stabilization of the SARS-CoV-2 Receptor Binding Domain by Protein Core Redesign and Deep Mutational Scanning

A. C. Leonard, J. Weinstein, P. J. Steiner, A. Erbse, S. J. Fleishman, T. A. Whitehead

The paper stabilizes the SARS-CoV-2 RBD using deep mutational scanning and computational design, resulting in a more thermally stable and proteolytically resistant variant.

bioRxiv · Nov 22, 2021Biochemistry

Coronacept - a potent immunoadhesin against SARS-CoV-2

H. Cohen-Dvashi, J. Weinstein, M. Katz, M. Eilon, Y. Mor, A. Shimon, R. Strobelt, M. Shemesh, S. J. Fleishman, R. Diskin

The paper describes the design of a modified human ACE2 immunoadhesin with enhanced affinity for SARS-CoV-2 spike protein, showing its potential as an antiviral agent.

bioRxiv · Aug 12, 2020 · PreprintBioengineering