Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
This study shows that heavy-tailed distributions of beneficial fitness effects lead to unpredictable, repeatable evolution, challenging the standard view of parallel evolution.
The paper models antibiotic resistance evolution in bacteria under changing environments using a driven disordered systems framework, revealing hysteresis and memory effects.
M. Saebelfeld, S. G. Das, J. Brink…·J. A. G. de Visser
The paper shows that susceptible bacteria breaking down antibiotics can increase the establishment of resistant mutants, despite their low enzymatic activity.
M. Saebelfeld, S. G. Das, A. Hagenbeek…·A. de Visser
The paper quantifies single-cell establishment probabilities of β-lactam resistant E. coli mutants under different antibiotic concentrations and environments, revealing stochastic effects and cooperative resistance mechanisms.
S. G. Das, S. O. L. Direito, B. Waclaw…·J. Krug
The paper develops a mathematical model of fitness landscapes shaped by adaptational tradeoffs, showing predictable properties and accessible evolutionary paths despite ruggedness.