Author

S. Haeflinger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Cristi· 1 shared H. E. Eaton· 1 shared I. Bernard· 1 shared J. Fernandes· 1 shared M. Hitt· 1 shared M. Shmulevitz· 1 shared P. Chen· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

F. Cristi

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1 paper

Recent·Most cited

Breast tumor-associated metalloproteases restrict reovirus oncolysis by cleaving the σ1 cell-attachment protein, and can be overcome by mutation of σ1

J. Fernandes, F. Cristi, H. E. Eaton, P. Chen, S. Haeflinger, I. Bernard, M. Hitt, M. Shmulevitz

This study shows that breast tumor-associated metalloproteases cleave reovirus σ1 protein, reducing infectivity, and demonstrates that a σ1 mutation can overcome this inactivation.

Journal of Virology · Nov 15, 2019Peer-reviewedMicrobiology