Author

S. Holtze

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Cellerino· 1 shared A. Sahm· 1 shared A. Weise· 1 shared C. Calkhoven· 1 shared C. Galli· 1 shared C. Mueller· 1 shared F. Goeritz· 1 shared H. A. Kestler· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperEvolutionary Biology

A. Cellerino

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2 papers

Recent·Most cited

Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros

V. Zywitza, S. Frahm, N. Krueger, A. Weise, F. Goeritz, R. Hermes, S. Holtze, S. Colleoni, C. Galli, M. Drukker, T. B. Hildebrandt, S. Diecke

The paper generates and characterizes induced pluripotent stem cells (iPSCs) from the Sumatran rhinoceros to aid in conservation efforts.

bioRxiv · May 12, 2022Cell Biology

Long-lived rodents reveal signatures of positive selection in genes associated with lifespan and eusociality

A. Sahm, M. Bens, K. Szafranski, S. Holtze, M. Groth, M. Goerlach, C. Calkhoven, C. Mueller, M. Schwab, H. A. Kestler, A. Cellerino, H. Burda, T. Hildebrandt, P. Dammann, M. Platzer

The paper identifies genes under positive selection in long-lived rodents, linking them to mTOR-related processes, immune function, and antioxidant defense, and finds expression patterns consistent with antagonistic pleiotropy in aging.

bioRxiv · Oct 8, 2017Evolutionary Biology