Hepatic lipid-associated macrophages mediate the beneficial effects of bariatric surgery against MASH
G. Fredrickson, K. Florczak, F. Barrow, K. Dietsche, H. Wang, P. Parthiban, R. Almutlaq, O. Adeyi, A. Herman, A. Bartolomucci, C. Staley, C. Jahansouz, J. W. Williams, D. Mashek, S. Ikramuddin, X. Revelo
This study shows that bariatric surgery reduces MASH through TREM2-expressing hepatic macrophages, independent of weight loss.
bioRxiv · Jun 11, 2023 · PreprintPhysiology