The SARS-CoV-2 envelope (E) protein forms a calcium- and voltage-activated calcium channel
L. H. Antonides, Q. W. Hurst, C. M. Ives…·U. Zachariae
This study identifies the SARS-CoV-2 E protein as a calcium- and voltage-activated ion channel that releases Ca2+ from the ER, suggesting it as a potential target for antiviral therapies.