Pharmacology & ToxicologybioRxiv
High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling
J. B. MacMillan, R. G. Linington, S. K. Hight…·S. Wei
This paper introduces a platform integrating phenotypic screening and metabolomics to improve mechanism of action prediction for natural products, leading to the discovery of novel bioactive compounds.
DOI 10.1073/pnas.2208458119