Cell BiologybioRxiv
A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia
R. A. Voit, L. Tao, F. Yu…·V. G. Sankaran
The paper studies a genetic disorder caused by MECOM haploinsufficiency to identify a transcriptional network critical for HSC maintenance, which is also co-opted in high-risk leukemias.