Molecular mechanism of tRNA binding by the Escherichia coli N7 guanosine methyltransferase TrmB
S. K. Schultz, K. Meadows, U. Kothe
The paper investigates the molecular mechanism of tRNA binding by E. coli TrmB using a fluorescent tRNA assay and kinetic measurements, revealing key residues and the role of SAM in binding and catalysis.
bioRxiv · Oct 29, 2022 · PreprintBiochemistry