Author

U. Kothe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

S. K. Schultz· 2 shared A. Henrickson· 1 shared A. Savelyev· 1 shared B. Demeler· 1 shared D. P. Czekay· 1 shared E. K. Kelly· 1 shared G. E. Gorbet· 1 shared J. Hargreaves· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

S. K. Schultz

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Author profile →

3 papers

Recent·Most cited

Molecular mechanism of tRNA binding by the Escherichia coli N7 guanosine methyltransferase TrmB

S. K. Schultz, K. Meadows, U. Kothe

The paper investigates the molecular mechanism of tRNA binding by E. coli TrmB using a fluorescent tRNA assay and kinetic measurements, revealing key residues and the role of SAM in binding and catalysis.

bioRxiv · Oct 29, 2022 · PreprintBiochemistry

Multi-Wavelength Analytical Ultracentrifugation of Biopolymer Mixtures and Interactions

A. Henrickson, G. E. Gorbet, A. Savelyev, M. Kim, S. K. Schultz, X. Ding, J. Hargreaves, V. Gradinaru, U. Kothe, B. Demeler

The paper demonstrates the utility of multi-wavelength analytical ultracentrifugation for analyzing complex biopolymer mixtures and interactions.

bioRxiv · Dec 29, 2021Biophysics

Base pairing interactions between substrate RNA and H/ACA guide RNA modulate the kinetics of pseudouridylation, but not the affinity of substrate binding by H/ACA small nucleolar Ribonucleoproteins

E. K. Kelly, D. P. Czekay, U. Kothe

This study shows that base pairing between H/ACA guide RNA and substrate RNA affects pseudouridylation kinetics but not binding affinity, providing insights into RNA recognition mechanisms.

bioRxiv · Jul 11, 2019Biochemistry